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Can CBD Oil Help with Seizures? 2024

Can CBD Oil Help with Seizures?

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Changes in electrical activity in your brain trigger seizures. Seizures come in a variety of forms, and probable causes include:

• Epilepsy
• Brain Infections
• Electrolyte Imbalances
• Sleep Deprivation
• Traumatic Brain Injury
• Drug Overdose

CBD Oil for Seizures and Epilepsy
Cannabidiol (CBD) is a substance contained in the cannabis plant that is commonly used to treat chronic pain and anxiety problems. CBD, unlike tetrahydrocannabinol (THC), is not euphoric or intoxicating.
 
CBD oil may be useful in the treatment of some types of seizures.
 
In this post, we will examine the current research findings as well as the potential negative effects.

How can CBD Oil help with seizures?

It is unclear how CBD helps prevent seizures.
 
The endocannabinoid system is a network of neurotransmitters and receptors in your body. This system is hypothesised to aid in the regulation of bodily processes such as hunger, sleep, and pain, as well as immune system response.
 
CBD may alter these processes by interacting with receptors in your endocannabinoid system.
 
According to animal studies, CBD’s antiseizure benefits may be due to its ability to reduce neuron excitability by acting on two types of receptors known as GPR55 and TRPV1 receptors.
 
The Food and Medicine Administration (FDA) has now authorised the prescription drug CBD Epidolex to treat Lennox-Gastaut and Dravet syndromes, two uncommon types of epilepsy. It is also authorised by the FDA for the treatment of seizures induced by the genetic condition tuberous sclerosis complex.

How effective is CBD Oil in treating seizures?

CBD oil’s efficacy to treat seizures is still being studied. The most rigorous studies have been conducted on persons suffering from one of the three illnesses for which CBD oil has been authorised by the FDA.

CBD for Seizures

CBD for Lennox-Gastaut syndrome

Lennox-Gastaut syndrome accounts for 2 to 5% of all paediatric epilepsy cases.
 
CBD was tested in two 14-week clinical studies for its effectiveness in treating seizures in patients with Lennox-Gastaut syndrome.

Study 1

Researchers examined the antiseizure impact of 20 milligram per kilogram (mg/kg) of CBD per day against a placebo in the first study.

They discovered:

  • Half of those who took CBD had 44% fewer seizures.
  • Half of those in the placebo group had 22% fewer seizures.

Study 2

The second trial evaluated the effects of CBD 10 mg/kg and 20 mg/kg daily doses to a placebo.
 
There were considerably fewer seizures in both CBD groups than in the placebo group.
 
  • Half of the subjects who took 20 mg/kg CBD daily had 42 percent fewer seizures.
  • Half of the subjects who received 10 mg/kg every day had 37% fewer seizures.
  • Half of the subjects in the placebo group had 17% fewer seizures.

CBD for Dravet syndrome

Dravet syndrome is an uncommon form of epilepsy characterised by seizures that are resistant to medication.
 
In a clinical investigation, researchers evaluated the efficacy of 20 mg/kg CBD administered daily to that of a placebo in children aged 2 to 18.
 
When compared to the placebo group, those who took CBD saw a substantial reduction in seizure frequency (39 percent) (17 percent decrease).

CBD for Tuberous Sclerosis Complex

Tuberous sclerosis complex is an uncommon illness that affects around one in every 6,000 people. It is a hereditary condition that causes noncancerous tumours to form throughout your body. Some patients experience seizures as a result of brain tumours.
 
In a clinical experiment, researchers evaluated the effects of CBD 25 mg/kg and 50 mg/kg per day to a placebo on 148 individuals with tuberous sclerosis complex.
 
The CBD group improved by 48 percent on average, whereas the placebo group improved by 24 percent.

CBD for other causes of seizures

More study is needed to determine whether CBD is beneficial in treating other types of seizures. However, preliminary research has yielded encouraging outcomes.
 
CBD appears to boost the impact of the epileptic medicine clobazam (Onfi), according to research. There is some evidence that CBD may increase the impact of other antiepileptic medications.
 
A 2018 study looked at the effects of CBD on 55 people suffering from one of four types of epileptic syndromes:
 
  • CDKL5 deficient syndrome
  • Aicardi disease
  • The Doose Syndrome
  • The Dup15q syndrome
At the start, the participants experienced 59.4 seizures each month on average. The average dropped to 22.5 per month after 12 weeks. The results remained for the whole 48-week period.

CBD for Seizures

How should CBD oil be used to treat seizures?

When utilising CBD oil to treat seizures, it is critical to consult with a doctor. Your doctor can advise you on if CBD will interact with any of your existing drugs.
 
According to research, some people experience more seizures after using CBD. Your doctor can assist you in monitoring your seizure frequency and determining whether CBD is appropriate for you.
 
Recommended beginning dosage is 2.5 mg/kg twice day. Following a week, the dosage can be raised to 5 mg/kg twice day. It can be raised to a maximum of 10 mg/kg twice per day based on an individual’s reaction and tolerability.
 
If you’re using CBD oil for seizures, don’t quit abruptly since it may cause an increase in seizures.

Can CBD interfere with or interact with other seizure medications?

Both CBD and other antiepileptic medicines may raise your risk of suicidal thoughts and acts. This occurs in around one in every 500 people.
 
CBD may interact with other seizure drugs. In rare situations, it may make the drug more or less effective. CBD is known to interact with the following medications:
 
  • Brivaracetam
  • Clobazam
  • Eslicarbazepine
  • Stiripentol
  • Rufinamide
  • Topiramate
  • Valproic Acid
  • Zonisamide

Unless your doctor instructs you differently, you should not use CBD to substitute standard drugs. Your doctor can assist you in adjusting the dosages of your prescription and CBD as needed.

What are the risks of using CBD to treat seizures?

The following are the most prevalent CBD side effects:
 
  • Sleepiness
  • Drowsiness
  • Appetite loss
When used with some drugs, CBD may raise the risk of liver damage. Whatever your reason for using CBD, it’s critical to choose a CBD oil that has been third-party tested for contaminants.

All CBD products offered on BritishCBD have been third-party tested to ensure that we are only promoting the highest-quality CBD. If you would like to view lab reports for any item, please send us an email using our contact form.
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Consult with a Doctor

If you want to use CBD oil to help manage your seizures, you should first consult with a doctor.
 
Your doctor can advise you on the best method to take CBD and whether it may interfere with any other drugs you’re taking.
 
They can also assist you in tracking your progress over time to see whether your seizure frequency is reducing.
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